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The increased pre-treatment gonadotropin levels (FSH and LH) found in our patients are likely related to a state of hypogonadism, causing aberration in the process of spermatogenesis, which improves with NAC supplementation as confirmed by the increase in serum testosterone levels

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Proc Natl Acad Sci U S A 2000, 97: 5071-5076

Contents Chemical properties Metabolism Energy cost of 2,3-bisphosphoglycerate synthesis Role of 2,3-bisphosphoglycerate Hemoglobin Cooperativity of hemoglobin-oxygen binding Hemoglobin affinity for oxygen 2,3-Bisphosphoglycerate and hemoglobin A 2,3-Bisphosphoglycerate and hemoglobin F Changes in 2,3-bisphosphoglycerate concentration Adaptation to high altitudes Anemia References Chemical properties 2,3-Bisphosphoglycerate is the conjugate base of 2,3-bisphosphoglyceric acid

Macrobius Saturnalia III 4 9